what's l-carnitine Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression NaturaLife Labs Acetyl L-Carnitine (ALCAR)

Autophagy 9 , 239240 (2013)

A., Gushikem, Y

Dihexa and its analogs bind with high affinity to HGF, induce Met phosphorylation in the presence of subthreshold levels of HGF, stimulate hippocampal spinogenesis and synaptogenesis equivalent with HGF [84], and promote neurogenesis and cerebroprotection (data in preparation for publication)

Recent studies have also focused on the fine regulatory mechanisms of inflammatory response, such as the activation of NLRP3 inflammasome in sensing various danger signals (Seoane et al., 2020), and the complex role of Hypoxia-inducible factors (HIFs) in regulating inflammation and immune response (Foglia et al., 2021)

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation